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Medical Science MDSC

MDSC 203 205 307 308 341 351 397 401 402 404 407 408 409 501 503 507 508 509 511 515 528 541 543 545 561 603 604 605 609 612 613 619 621 623 627 629 631 633 635 637 638 639 641 642 643 644 645 647 649 651 657 659 660 661 663 668 669 670 671 672 673 674 675 676 677 678 679 683 685 689 701 703 705 706 707 708 709 711 712 713 717 721 731 733 735 737 739 751 755

Instruction offered by members of the Faculty of Medicine.

Students contemplating taking any of the undergraduate medical science courses are advised to contact the course coordinator(s) through the Undergraduate Sciences program office.Â Students contemplating taking any of the graduate-level (600- and up) Medical Science courses are advised to contact the course coordinator through the Graduate Science Education office.

Junior Courses

Medical Science 203

Developing Health Research Literacy I

Students will be introduced to the interdisciplinary scope of health research through reading and writing assignments.Â Students will learn the basics of academic research enquiry and practice academic writing and presentation skills through individual and team assignments.

Course Hours: H(3-2T)
Prerequisite(s): Admission to the BHSc Honours program.

Medical Science 205

Developing Health Research Literacy II

Students will develop their critical thinking skills and their ability to write logically, well-argued research papers. Students will learn the fundamentals of logical reasoning as well as how to analyze theoretical issues in science, medicine, and philosophy.
Course Hours: H(3-0)
Prerequisite(s): Medical Science 203 and admission to the BHSc Honours program.

Senior Courses

Medical Science 307

Science, Philosophy and Society

A survey of underlying ideas concerning the objectives, methods, ambitions and responsibilities of the natural and social sciences.
Course Hours: H(3-0)
Prerequisite(s): Second year or higher in the BHSc Honours program or consent of the Faculty.

Medical Science 308

Interdisciplinary Research Approaches

An introduction to the questions, methods and research techniques used across the different majors of Biomedical Sciences, Bioinformatics and Health and Society. Sessions will support the development of a broad perspective on health issues. A component of the course will also explore concepts in fact-value distinctions and ethical issues in research.
Course Hours: F(6-0)
Prerequisite(s): Medical Science 205 and admission to the BHSc Honours program.

Medical Science 341

Principles of Human Genetics

Introduction to principles in human genetics including Mendelian and chromosomal basis of inheritance, chromosomal abnormalities, pedigree analysis, mutations, and molecular, metabolic, population and clinical genetics. Studies of model organisms and genomics will be included as required. Incorporates problem-based learning to establish analytical skills in genetics.
Course Hours: H(3-2T)
Prerequisite(s): Biology 231 and Enrolment in the BHSc Honours program or consent of the Instructor.

Medical Science 351

Honours Cellular and Molecular Biology

Introduction to principles in cellular and molecular biology. Emphasizes how structure underlies and determines function in the cell and how complex processes are organized and regulated at the molecular level.
Course Hours: H(3-2T)
Prerequisite(s): Medical Science 341 and enrolment in the BHSc Honours program, or consent of the Faculty.
Corequisite(s): Biochemistry 393.
Antirequisite(s): Credit for both Medical Science 351 and Biological Science 331 will not be allowed.

Medical Science 397

Independent Studies in Health Sciences

Guided work fostering independent thought, practical research and the completion of written reports for first and second year BHSc students. After consultation with a Departmental faculty member who will supervise the chosen problem, an approval form obtained from theÂ BHScÂ Office must be signed by the Associate Dean (BHSc Office) before a student can be registered.
Course Hours: H(0-4)
Prerequisite(s): First or second year standing and consent of the BHSc Department.
MAY BE REPEATED FOR CREDIT

Medical Science 401

Bioinformatics

This introductory course will familiarize students with algorithms and computational techniques for bioinformatics applications. Topics to be covered include algorithm and search engines for the analysis of nucleic acid and protein sequences and structures; machine learning techniques for biological data analysis; systems biology approaches for computational modeling.
Course Hours: H(3-0)
Prerequisite(s): One full-course equivalent in Computer Science at the 300 level or one full-course equivalent in Biological Sciences at the 300 level or consent of the Department.

Medical Science 402

Organismal Biology

Organismal structure from the cellular to the organism level focusing on vertebrates with a particular emphasis on humans. Topics covered include cell biology, histology, vertebrate development and anatomy. This course is inquiry based and will consist of lectures, small group sessions and interactive laboratory sessions.
Course Hours: F(3-3)
Prerequisite(s): Enrolment in the BHSc Honours program, Biology 231, and Medical Science 351, or consent of the Faculty.

Medical Science 404

Integrative Human Physiology

Physiology is defined as the study of how living organisms function and encompasses the integration of processes from molecules to the whole-organism. Provides fundamental principles and concepts about the physiology of the major human organ systems. Each Unit is coordinated and taught by published scholars.
Course Hours: F(3-3T)
Prerequisite(s): Enrolment in the BHSc Honours program or consent of the Faculty.
Notes: Lectures run concurrently with Medical Science 604.

Medical Science 407

Statistics and Research Design in Health Sciences

An introduction to the study of research design and statistical analysis including a broad overview of the variety of methods for research in health sciences. Students will be introduced to a variety of research tools through lecture and tutorial components.
Course Hours: H(3-1T-2)
Prerequisite(s): Enrolment in the BHSc Honours program.

Medical Science 408

Research Design in Molecular Biology and Bioinformatics

An introduction to the research methods utilized in the Health Sciences. Students will begin to develop the knowledge and skills necessary to conduct research in their respective fields. The importance of research design, qualitative, quantitative and mixed methods and the theoretical constructs that inform these approaches will be emphasized.
Course Hours: F(6-0)
Prerequisite(s): Medical Science 308 and admission to the BHSc Honours program.

Medical Science 409

Brain and Society

Topics will include neuronal mechanisms of addiction, neuronal mechanisms of learning and memory, aging in the human brain and behavioural consequences and mind/brain dichotomy.
Course Hours: H(3-0)
Prerequisite(s): Enrolment in the BHSc Honours program.

Medical Science 501

Principles and Mechanisms of Pharmacology

Basic principles of pharmacology, with specific emphasis on receptor signaling mechanisms.
Course Hours: H(3-0)
Prerequisite(s): Enrolment in the BHSc Honours program, Biochemistry 443, and one of Zoology 461, 463, or Medical Science 404, or consent of the Faculty.
Also known as: (Biology 501)

Medical Science 503

Pharmacology of Organ Systems

Pharmacology of the nervous, cardiovascular, renal and immune systems, as well as anti-cancer therapies. Principles of toxicology.
Course Hours: H(3-0)
Prerequisite(s): Medical Science 501 (Biology 501) or consent of the Faculty.
Also known as: (Biology 503)

Medical Science 507

Special Problems in Medical Science

Lectures, seminars, term papers and training in theoretical and/or laboratory methods. After consultation with a faculty member who will supervise the chosen problem, an approval form obtained from the Graduate Sciences Education Office must be signed by the Associate Dean (Graduate Sciences Education) before a student can register.
Course Hours: H(3-3)
Prerequisite(s): Consent of the BHSc Honours Department.
MAY BE REPEATED FOR CREDIT

Medical Science 508

Honours Thesis and Research Communication

Capstone research course in the BHSc to be conducted through any one of the basic research departments. Students would be expected to conduct research. Culminates with a Research Symposium Day during which students present and defend their research before an audience of peers and mentors, share their research with the faculty and staff at large through poster presentations and submit a written research thesis.
Course Hours: 2xF(0-6)
Prerequisite(s): Enrolment in the BHSc Honours program and Health and Society 408 or Medical Science 408 or approval of the Department.
Notes: This course is worth 2.0 FCE and is only offered over two sessions.

Medical Science 509

Proteomics

An introductory course to familiarize students with techniques used for protein identification and proteome analysis, including one and two-dimensional gel electrophoresis, mass spectrometry and the databases and search engines used in the identification of expressed proteins.
Course Hours: H(3-3)
Prerequisite(s): Biochemistry 443 and Biology 331.

Medical Science 511

Instrumental Analysis

An overview of the analytical laboratory instruments used in research and the diagnosis and treatment of human disease.
Course Hours: H(3-0)

Medical Science 515

Cellular Mechanisms of Disease

The cellular and molecular mechanisms underlying basic human disease processes and how these can be influenced by lifestyle and environmental factors. The ways in which this knowledge can be used in the laboratory diagnosis of disease.
Course Hours: H(3-0)
Prerequisite(s): Biochemistry 443 and one of Biology 331 or Medical Science 351.
Also known as: (Biology 515)

Medical Science 528

Independent Studies in Medical Science

Original and independent thought, practical research and the completion of written and oral reports. After consultation with a faculty member who will supervise the chosen problem, an approval form obtained from the Graduate Sciences Education Office must be signed by the Associate Dean (Graduate Sciences Education) before a student can register.
Course Hours: F(0-6)
Prerequisite(s): Consent of the BHSc Department.
MAY BE REPEATED FOR CREDIT

Medical Science 541

Advanced Genetics I

Historical papers will illustrate the foundations of modern genetic principles. Topics including the chromosomal theory of inheritance, the role of pairing and recombination for chromosomal disjunction during meiosis, cytogenetics, the nature of dominant mutations, genetic screens and genetics analysis of developmental pathways. Material covered is drawn from model organisms and humans.

Course Hours: H(3-0)
Prerequisite(s): Medical Science 341 or Biology 311 or consent of the Faculty.
Notes: Lectures run concurrently with Medical Science 641.01.

Medical Science 543

Advance Genetics II

An advanced course in molecular genetic analysis. Topics will vary from year to year, but may include identification of the structure, transmission, mutation and molecular pathology of human genes, the use of experimental organisms (chick, fish, fly, mouse, worm) to model human genetic diseases, and molecular studies of human populations and evolution. The focus will be upon applied molecular genetics with recurring emphasis on the theme of relevance to issues in health and society.
Course Hours: H(3-0)
Prerequisite(s): Medical Science 341, 402 or permission of the instructor.
Notes: Lectures run concurrently with Medical Science 641.03. Previous completion of Medical Science 541 is suggested but not required.

Medical Science 545

Genomics

Course Hours: H(3-0)
Prerequisite(s): Medical Science 341 or Biology 311 or consent of the Faculty.
Notes: Lectures run concurrently with Medical Science 641.04.

Medical Science 561

Cancer Biology

Advances in methodology and in theoretical concepts have permitted continuing breakthroughs in our understanding of the organismal, cellular and molecular biology of cancer cells, and in the development of novel strategies for cancer prevention, diagnosis and treatment. These advances will be presented in a comprehensive overview of cancer including issues of demographics and incidence, causation and detection, origins and progression and therapeutic approaches. Emphasis will be placed on the cell and molecular biology of cancer and on the interaction of the cancer cell with the host organism.
Course Hours: H(3-0)
Prerequisite(s): Biochemistry 443, Biology 331, and Cellular, Molecular and Microbial Biology 411.
Also known as: (Cellular, Molecular and Microbial Biology 561)

Graduate Courses

Medical Science 603

Biology of Laboratory Animals

The course is based on the Canadian Council of Animal Care Syllabus "Basic Principles of Laboratory Animal Science for Research Scientists." In addition to the study of common, research, farm and exotic animals, topics covered include ethical considerations, regulation and legislation, animal models, animal facilities and husbandry, hazard control, surgery, anaesthesiology, euthanasia and post-mortem examinations. Practical sessions will provide experience in handling and restraint of specific laboratory animals, injections, blood collection, anaesthesiology and surgery.
Course Hours: H(3-1)
Prerequisite(s): Consent of the Faculty.
Notes: Enrolment in this course is restricted to graduate students who will do research utilizing animals.
Also known as: (Biology 603)

Medical Science 604

Integrative Human Physiology

Physiology is the study of how living organisms function and encompasses the integration of processes from molecules to the whole-organism. Designed to provide the student with fundamental principles and concepts about the normal function of the major human organ systems. At the end of this course, the student should be well equipped to apply his/her acquired knowledge to solve complex physiological problems related to integrative human physiology.
Course Hours: F(3-3)
Prerequisite(s): Consent of the Faculty.
Notes: Lectures run concurrently with Medical Science 404.

Medical Science 605

Information Storage and Processing in Biological Systems

Examination of complex biological systems; concepts and fundamentals of biological solutions to information storage and processing: modelling and computer simulation of biological systems; information storage in biological molecules; genetic networks; hierarchical organization of biological information processing in signal transduction, development, evolution, and ecology; biological control systems.
Course Hours: H(3-0)
Prerequisite(s): Consent of the Faculty.
Also known as: (Computer Science 605)

Medical Science 609

Gene Expression

The flow of genetic information from DNA to final protein product. The subject will be covered in two courses offered in alternating years: gene structure and regulation of transcription, including gene structure and organization, chromatin structure, regulation of transcription and post-translational processing; and the activity of genes during development including stored messenger ribonucleoprotein particles and translational control in gametes, the switch from maternal to zygote genome control of development in early embryos and the molecular basis of morphogenesis and differentiation.

609.02. Genes and Development

Course Hours: H(3-0)
Prerequisite(s): Medical Science 537 (Biochemistry 537) or equivalent and consent of the Faculty.
Antirequisite(s): Credit for both Medical Science 609.01 and 607.01 will not be allowed. Note: Credit for both Medical Science 609.02 and 751.14 will not be allowed.

Medical Science 612

Medical Microbiology

The basic principles of medical microbiology and the pathogenesis of infectious disease and of clinically important microbial pathogens including bacteria, viruses, parasites and fungi. Recent concepts will be described and students will be expected to present and critically discuss research advances of their choosing from the current research literature.
Course Hours: F(1S-3)
Prerequisite(s): Cellular, Molecular and Microbial Biology 241 and 343 or equivalent or consent of the Faculty.

Medical Science 613

Advanced Studies in Microbiology

Specialized topics including basic principles of infection; spread, prevention and control of infectious diseases; mechanisms of and approaches to study bacterial pathogenesis; mechanism, methodology and modelling of gene expression.

613.01. Epidemiology of Infectious Diseases

613.02. Pathogenesis of Microbial Disease

613.05. Regulation of Gene Expression in Bacteria

Course Hours: H(3-0)
Prerequisite(s): Medical Science 612 or Cellular, Molecular and Microbial Biology 421 or 521 or consent of the Faculty.

Medical Science 619

Neurosciences

Introductory neuroscience courses covering aspects of cellular, molecular, and systems physiology, neuroanatomy, and neurodevelopment.

619.01. Cellular and Molecular Neuroscience

619.02. Systems Neuroscience

619.03. Developmental Neuroscience

619.04. Neuroanatomy

Course Hours: H(3-0)
Prerequisite(s): Consent of the Faculty.
Notes: Medical Science 619.02 is open only to graduate students registered in the Neuroscience graduate program or other graduate students approved by the course coordinator. Not open to undergraduate students.

Medical Science 621

Principles of Drug Action

The action of chemicals and drugs on biological systems ranging from subcellular particles to the intact organism.

621.01. Basic Principles of Pharmacology

Course Hours: H(3-0)
Prerequisite(s): Zoology 461 and Biochemistry 441 and 443 or consent of the Faculty.

Medical Science 623

Respiratory Science and Critical Illness

Respiratory physiology; including topics such as cellular, morphology, mechanics, control of breathing, and respiratory muscles,Â necessary to an understanding of respiration and respiratory failure.Â As well, core physiology and molecular biology underlying critical illness.Â

623.01. Pulmonary Mechanics and Gas Exchange

623.02. Physiology of Respiration and Critical Illness

623.03. Respiratory Science: Basic

623.04. Respiratory Science: Applied

Course Hours: H(3-1T)
Prerequisite(s): Zoology 463 or 465 or consent of the Faculty.

Medical Science 627

Endocrinology

Normal endocrine physiology and biochemistry. Mechanisms and principles of departure from normal endocrine homeostasis.

627.03. Selected Topics in Advanced Endocrinology

Course Hours: H(3-0)
Prerequisite(s): Zoology 597 or consent of the Faculty.

Medical Science 629

Cardiovascular Dynamics

Includes topics such as basic physiologic mechanisms including excitation-contraction coupling, mechanics, energetics, and cardiovascular control; major diseases entities as a means of illustrating pathologic alterations in normal physiologic mechanisms; or a systematic in-depth examination of the chemicals that affect the cardiovascular system.

629.01. Cardiovascular Physiology

629.02. Cardiovascular Pathophysiology

629.03. Cardiovascular Pharmacology

Course Hours: H(3-0)
Prerequisite(s): Consent of the Faculty.

Medical Science 631

Muscle Physiology

Contractile processes, excitation-contraction coupling, the control of contraction and energetics in smooth, cardiac and skeletal muscle. Molecular studies of the contractile process and of the process of excitation contraction coupling.
Course Hours: H(3-0)
Prerequisite(s): Consent of the Faculty.

Medical Science 633

The Kidney

Advanced courses detailing the functional organization of the kidney at all levels, from cell to intact organism. Topics encompass basic physiological principles and their relevance to experimental medicine and therapeutics, as well as the study of disease processes, which impact kidney function.

633.01. Renal Physiology

633.02. Renal Pathophysiology

Course Hours: H(3-0)
Prerequisite(s): Medical Science 604 or equivalent or consent of the Faculty.

Medical Science 635

Psychosocial Oncology

Focuses on developing the understanding in health care practitioners of the central concepts related to caring for cancer patients and their families. In doing so, makes use of lectures, readings, video tapes, case discussions, and current research.
Course Hours: H(3-0)
Prerequisite(s): Consent of the Faculty.
Antirequisite(s): Credit for both Medical Science 635 and 645.14 will not be allowed.

Medical Science 637

Gastrointestinal Physiology

Physiology of the gastrointestinal (GI) tract at all levels from the cell to the intact system. Medical Science 637.01 has three components 1) An introductory series of lectures covering the basic physiological principles of the regulation of the GI tract and the individual organs that comprise it or are associated with it. 2) Extended directed tutorials conducted on-line through Blackboard. Topics will be selected to reflect the needs and interests of the enrolled students. 3) A written term paper on a subject of the students' own choice and pre-approved by the course coordinator that will also be presented orally to the class.

637.01. Organization and Function of the GI Tract

Course Hours: H(3-0)
Prerequisite(s): Consent of the Faculty.

Medical Science 638

Mucosal Pathophysiology

An independent study course that focuses on the physiology and pathophysiology of the gastrointestinal tract, lung and other mucosal tissues. A particular emphasis will be placed on inflammatory processes in these tissues, and how they contribute to symptom generation and tissue dysfunction. Involves independent research on the part of the students, small group tutorials, written assignments and laboratory exercises. The course will be divided into three sections.
Course Hours: H(3-0)
Notes: Medical Science 637.01 recommended.

Medical Science 639

Immunology

Introductory and advanced courses in immunology that cover humoral and cellular immunity and the inflammatory response at the cellular, molecular, and whole organism level. Basic mechanisms that lead to immunity or to inflammatory responses. The contribution of immunological and inflammatory processes in the immunopathogenesis of disease.

639.01. Principles of Immunology

639.02. Cellular and Molecular Immunology

639.03. Topics in Immunology

639.04. Inflammation

Course Hours: H(3-0)
Prerequisite(s): Consent of the Faculty.
Antirequisite(s): Credit for both Medical Science 639.01 and 755.01 will not be allowed. Credit for both Medical Science 639.02 and 641.01 will not be allowed. Credit for both Medical Science 639.03 and 641.03 will not be allowed. Credit for both Medical Science 639 and 639.04 will not be allowed.

Medical Science 641

Genetics

Advanced courses that provide in depth coverage of the research discipline of genetics, including the areas of cytogenetics, genomics, metabolic genetics, mouse genetics, population genetics, and human and medical genetics.

641.01. Advanced Genetics I

641.02. Advanced Human Cytogenetics

641.03. Advanced Genetics II

641.04. Genomics

Course Hours: H(3-0)
Prerequisite(s): Consent of the Instructor.

Medical Science 642

Determinants of Health I

As an important research foundation in this department, the course is intended to provide an understanding of the determinants of health within a population health framework.
Course Hours: H(3-0)
Prerequisite(s): Admission to a graduate program in the Department of Community Health Sciences or the Community Medicine Residency Program.
Notes: This winter block week course is a requirement for all thesis-based MSc and PhD students in graduate programs in the Department of Community Health Sciences.
Also known as: (formerly Medical Science 644.02)

Medical Science 643

Biostatistics

Focuses on the key methods necessary to understand and critically interpret results from common biostatistical analyses, as well as, gaining hands-on experience analyzing data using statistical software. Medical Science 643.01 introduces the fundamental concepts of summarizing data and statistical inference, including graphical displays, hypothesis testing, p-values, confidence intervals, and sample size determination. Medical Science 643.02 extends the fundamental concepts to modelling health outcomes using modern regression analysis techniques. Logistic and linear regressions, and their extensions, are covered in detail. Medical Science 643.03 broadens the techniques to include generalized linear models (GLM), generalized additive models (GAM), Poisson regression, generalized estimating equations (GEE), and proportional hazards regression.Â

643.01 Biostatistics I: Essentials of Biostatistics

643.02 Biostatistics II: Models for Health Outcomes.

643.03. Biostatistics III: Models for Repeated Measures Studies and Time-to-Event Studies

Course Hours: H(3-2)
Prerequisite(s): Admission to a graduate program in Community Health Sciences or the Community Medicine Residency Training Program is required. Medical Science 643.02 requires either 643.01 or a graduate-level introductory course in (bio)statistics. Medical Science 643.03 requires Medical Science 643.02.
Notes: Medical Science 643.01 requires no formal prerequisites but good quantitative and mathematical skills are an asset. Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other graduate and undergraduate students. These courses are not available to Open Studies students.

Medical Science 644

Introduction to Community Health Sciences

It is intended to provide an introduction to the Department and a general orientation to the education and research programs in Community Health Sciences.

Course Hours: H(3-0)
Prerequisite(s): Admission to a graduate program in the Department of Community Health Sciences or the Community Medicine Residency Program.
Notes: This fall block week course is a requirement for all thesis-based MSc and PhD students entering graduate programs in the Department of Community Health Sciences.
Also known as: (formerly Medical Science 644.01)
NOT INCLUDED IN GPA

Medical Science 645

Health Services Research

Health services research is a multidisciplinary field of scientific investigation, both basic and applied, that studies how social factors, financing systems, organizational structures and process, health technologies and personal behaviours affect access to health care, the quality and cost of health care, and ultimately our health and well-being.

645.01. Systems of Health and the Health Care System

645.10. Leadership in Health Care Organizations

645.15. Health Policy: Policy Issues in the Canadian Health Care System

645.17. Introduction to the Legal and Ethical Framework of Health Care in Canada

645.18. Foundations of Health Services Research

Course Hours: H(3-0)
Notes: Admission to a graduate program in Community Health Sciences is normally required. Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other graduate and undergraduate students.

Medical Science 647

Epidemiology

Epidemiology is the study of the distribution of diseases in populations and of factors that influence the occurrence of disease.Â Courses focus on principles and methods of descriptive, analytic and experimental epidemiology, as well as epidemiological methods specific to certain health conditions and the preventive strategies available for various health conditions.

647.01. Fundamentals of Epidemiology

647.05. Epidemiology of Aging

647.07. Research in Healthcare Epidemiology and Infection Control

647.09. Epidemiology of Chronic Diseases

647.10. Surveillance 1: Data Handling for Infection Control

647.11. Surveillance 2: Principles of Surveillance

647.12. Introduction to Population Health Surveillance

647.15 Clinical Epidemiology

Course Hours: H(3-2)
Prerequisite(s): Medical Science 643.01 or consent of the Faculty.
Notes: Admission to a graduate program in Community Health Sciences is normally required. Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other graduate and undergraduate students. These courses are not available to Open Studies students.

Medical Science 649

Practicum in Community Health Sciences

Clinical or field-based practicum for students enrolled in certain programs of the Department of Community Health Sciences.

649.01. Practicum in Community Medicine

649.02. Practicum in Healthcare Epidemiology

649.03. Practicum in Community Health Sciences Specialization

Course Hours: H(1-3)
Notes: Admission to a graduate program in Community Health Sciences is normally required. Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other graduate and undergraduate students.
NOT INCLUDED IN GPA

Medical Science 651

Population/Public Health

The courses within the Population/Public Health family are intended to provide graduates the opportunity to gain the competencies required to become researchers, planners, and practitioners in fields that require a depth of understanding of the determinants of health, the values and philosophies of population and public health, behaviour change theory, and the role of the ecosystem in promoting and protecting the health of the public.

651.01. Health Promotion Planning

651.02. Health Promotion for Women

651.03. Community Interventions: Theory, Research and Practice

651.04. Foundations of Population/Public Health

651.05. Determinants of Health II

651.06. Environmental Health

651.07. Health of Canadian Aboriginal Peoples

651.08. Global Health and Development

Course Hours: H(3-0)
Prerequisite(s): Medical Science 647.01 is a prerequisite for Medical Science 651.06.
Notes: Admission to a graduate program in Community Health Sciences is normally required. Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other graduate and undergraduate students. Medical Science 651.06: one or more field trips may be required outside regular class time.

Medical Science 657

Telehealth and E-health

These online courses explore many aspects of e-health, beginning with an initial focus on telehealth. They reflect a range of practice-based activities and research areas in e-health including business plan development, implementation and evaluation of clinical and learning applications.

657.02. e-Health Sustainability: From Business Case to Policy Development

657.03. Evaluation of e-Health Initiatives

Course Hours: H(3-0)
Prerequisite(s): Admission to a graduate program in Community Health Sciences is normally required. Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other graduate and undergraduate students.
Notes: These are online courses.

Medical Science 659

Research Methods

An introduction to research design, sampling, measurement, data collection and data analysis applied to research in community health sciences.

659.02. Health Research Methods

659.03. Health Program Planning and Evaluation

659.04. Introduction to Clinical Trials

659.05. Qualitative Health Research

659.06. Decision Analysis in Health Economic Evaluation

659.07. Administrative Data Analysis Methodology

659.08. Economic Evaluation

Medical Science 660

On-line Basic Infection Control

Provides novice Infection Control Professionals (ICPs) with the basic knowledge, tools and strategies needed to do Infection Control in a broad range of health care environments from health care institutions to the community. The purpose of this entry to practice course is 1) to identify and describe the scope of infection prevention and control problems and issues for novice ICPs and 2) to examine and integrate their current expertise with the basic knowledge, tools and strategies needed to examine problems and develop practical solutions in Infection Control.
Course Hours: F(3-1.5)
Prerequisite(s): Admission to a graduate program in Community Health Sciences is normally required. Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other graduate and undergraduate students.

Medical Science 661

Science Value and Philosophy

Philosophical issues which fall into two categories: the Nature of Scientific Inquiry and Science and Moral Value.
Course Hours: H(3-0)
Prerequisite(s): Admission to a graduate program in Community Health Sciences is normally required. Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other graduate and undergraduate students.

Medical Science 663

Advanced Biomechanics

Theoretical and applied aspects of biomechanics in the acquisition and performance of sport skills.
Course Hours: H(3-0)
Prerequisite(s): Consent of the Faculty.
Also known as: (Kinesiology 663) (Mechanical Engineering 663)

Medical Science 668

Biotechnology Commercialization

Technology commercialization is the process of translating research results, scientific discoveries or processes and methods into a commercially useful and profitable product. Students will study the biotechnology commercialization process and will develop a mock-up i) starting with a new product or service idea, ii) carrying out the early stage development, iii) developing the necessary strategic and business plans, iv) securing adequate and appropriate financing, and v) marketing and selling the product. The primary deliverable will be the creation of a strategic plan for an innovative biotechnology product or service.
Course Hours: H(3-3)
Prerequisite(s): Consent of the Faculty.
Notes: Registration in Medical Science 672 or admission to the Master of Biomedical Technology, Biomedical Engineering MEng(T) or Master of Business Administration (with a prior BSc) program is suggested for enrolment in this course. Can be taken concurrently with Medical Science 672.

Medical Science 669

Clinical Trials and Bio-manufacturing

The objective of this course is to provide general understanding and appreciation, regulatory requirements and ethical considerations around conducting clinical trials as well as bio-pharmaceutical manufacturing. An emphasis will be placed on regulatory obligations. The course will provide opportunities in writing protocols, clinical trial applications, auditing facilities and process validation.

669.01. Laboratory TechniquesÂ and Commercial Applications

669.02. Bio-manufacturingÂ and Clinical Trials

Course Hours: Q(1.5-1.5T-3)
Prerequisite(s): Consent of the Course Coordinators.
Notes: Admission to MBT program is normally required for taking this course.

Medical Science 670

Practicum in Biomedical Technology

A full course carried out in an academic or industrial setting for a period of at least twelve weeks. Students have an opportunity to apply the principles and methods of investigation learned during the Master of Biomedical Technology program and carry out related research. Practicum projects can be focused on any of the following aspects of the commercialization process: patent filing, research and development, business development, manufacturing to clinical trials, marketing and sales.
Course Hours: F(0-6)
Prerequisite(s): Consent of the Faculty.
Notes: Completion of all other course requirements in Master of Biomedical Technology program is normally required prior to registration for this course.
NOT INCLUDED IN GPA

Medical Science 671

Techniques in Medical Science

Introduction to the theory of operation of electronic devices commonly used in biophysical studies including principles of amplifiers and filters, micro- and patch electrode techniques and computer-laboratory interfacing.
Course Hours: H(0-6)
Prerequisite(s): Consent of the Faculty.
MAY BE REPEATED FOR CREDIT

Medical Science 672

Biotechnology Business Aspects

Aspects involved in taking an original scientific idea or discovery all the way to a start-up company will be covered. Lecturers discuss commercialization, venture capital, business plan, patents and law, marketing.
Course Hours: H(2-0)
Prerequisite(s): Consent of the Biomedical Technology Graduate Coordinator.
Notes: Admission to the Master of Biomedical Technology program is normally required for enrolment in this course.

Medical Science 673

Careers in Biotechnology

A series of talks and workshops designed to provide students with practical knowledge of the biotechnology industry. In collaboration with the ²ÝÝ®ÎÛÊÓÆµµ¼º½ Career Services, the course covers personal and professional development planning, resume writing, networking, negotiation and interviewing skills and job search strategies specifically for the biotechnology field. This course runs during the fall and winter block weeks with additional retreat days throughout the year.
Course Hours: H(3S -0)
Notes: Admission to the Master of Biomedical Technology program is normally required for enrolment in this course.

Medical Science 674

Integrated Systems Course

The principles of molecular and cell biology, pathology, physiology, pharmacology, microbiology and immunology as applied to new diagnostics, vaccines or therapeutics. Lectures in the two courses are in parallel and fully integrated. Both courses are required components of the MBT program. The goal of the course, with an emphasis on cellular and molecular mechanisms in health and disease, is to provide students with the skills to interface with individuals in these disciplines in the biotechnology industry. Complemented by special lectures that provide industry perspectives in these disciplines.

674.01. Physiological and Pharmacological Aspects of Therapeutics Development

674.02. Molecular Cell Biology of Diagnostic and Vaccine Development

Course Hours: F(3-0)
Prerequisite(s): Consent of the Faculty.
Notes: Admission to the Master of Biomedical Technology program is required for enrolment in either section of this course.

Medical Science 675

Bioinformatics Resources for the Biologist

This introductory graduate level course will familiarize biologists with algorithms and search engines used to analyze nucleic acid and protein sequences and structures.
Course Hours: H(2-3T)
Prerequisite(s): Consent of the Faculty.

Medical Science 676

Scripting and Database Querying for Molecular Biologists

Intended for biologists who wish to improve their bioinformatics analysis capabilities by learning just a small amount of query and programming syntax. The focus is on practicality rather than programming theory. The course explores how to use existing tools (on the command-line and on the Web) to gather and process large datasets all at once, rather than doing many individual analyses manually.
Course Hours: H(2.5-1)
Notes: No prior programming experience is required.

Medical Science 677

Directed Study in Biomedical Technology

Lectures, seminars, term papers or training in theoretical and/or laboratory methods at the advanced level in biomedical technology or medical sciences.
Course Hours: H(1-6)
Prerequisite(s): Consent of both the faculty member who will supervise and the MBT faculty member who will co-supervise the chosen study.
Notes: Admission to the Master of Biomedical Technology program is required for enrolment in this course.
MAY BE REPEATED FOR CREDIT

Medical Science 678

Project in Biomedical Technology

Students will conduct both business and laboratory-based projects throughout the year.Â The business-based aspect will include running a business, doing market research for companies or working with their business mentor.Â The laboratory-based aspect will include new diagnostics development and validation. This course will cover basic principles of project management as well as biotech lab theory and practical aspects covered via tutorials, journal club and laboratory sessions.Â There will be a combination of monthly meetings, lectures, lab tutorials, commercial technology reviews, tours, demos, and practical labs.

Course Hours: H(1-3T-6)
Prerequisite(s): Consent of the Faculty.
Notes: Admission to the Master of Biomedical Technology program is required for enrolment in this course.

Medical Science 679

Health Economics I

Applies basic concepts from economics to the examination of health and health care policy issues such as why we have the kind of health care system we have, various aspects of health care reform, promotion of health, and evaluation in interventions.
Course Hours: H(3-0)
Notes: Enrolment is open to all MDCH graduate students. Consent of the Instructor is required for all other students.
Also known as: (Economics 679)

Medical Science 683

The Biology and Therapy of Human Cancer

An examination and discussion of current knowledge of the molecular and cellular biology of human cancer and the scientific basis of cancer therapy. Offered in a modular format: each course will consist of one required module and two elective modules. Students can choose the elective modules from a list that is specific for each course. Modules will emphasize student presentations, critical evaluation, and discussions of current and seminal research papers on the module topic. Refer to the Southern Alberta Cancer Research Institute website at www.sacri.ucalgary.ca for more information.

683.01. Cancer Pathology, Epidemiology and Therapy

683.02. Molecular Mechanisms of Cancer

683.04. Cell Biology of Cancer

Course Hours: H(3-0)
Prerequisite(s): Consent of the Faculty.

Medical Science 685

Biomechanics of Human Movement

Introduction to the measuring methods (accelerometry, goniometry, film and film analysis, video systems) of biomechanical analysis of human movement (force and force distribution). Description of the mechanical properties of bone, tendon, ligaments, cartilage, muscles, and soft tissues. The relation between structure and function of biomaterials. Introduction in descriptive analysis of human movement.
Course Hours: H(3-3)
Prerequisite(s): Consent of the Faculty.
Antirequisite(s): Credit for more than one of Medical Science 685, Mechanical Engineering 685 and Kinesiology 685 is not allowed.
Also known as: (Mechanical Engineering 685)

Medical Science 689

Medical Imaging

Introduction to the theory and practical applications of medical imaging. Specific courses focus on an overview of modern diagnostic imaging techniques (689.01), as well as advanced study of specific techniques including magnetic resonance imaging (689.02) and medical image processing (689.03), and molecular imaging (689.04).

689.01. Medical Imaging Techniques

689.02. Advanced Magnetic Resonance Imaging

689.03. Advanced Medical Image Processing

689.04. Advanced Molecular Imaging

689.99. Medical Imaging Project

Course Hours: H(3-0)
Prerequisite(s): Consent of the Faculty. Medical Science 689.01 should be taken prior to the advanced courses.
Notes: Courses are open to interested graduate students in medicine, engineering, and science and to appropriately prepared undergraduate students enrolled in computer engineering, electrical engineering, and physics.

Medical Science 701

Advanced Topics in Reproductive Health

A series of topics, ranging from basic sciences to clinical topics (including ethical issues) to increase awareness and comprehension regarding current issues in reproductive health.
Course Hours: H(3-0)
Prerequisite(s): Interest in reproductive health/reproductive biology. Consent of course co-ordinator and student's supervisor, if applicable.
Also known as: (Veterinary Medicine 701)

Medical Science 703

Human Anatomy: Concepts, Exploration and Teaching

Introductory course for graduate students with an interest in mammalian morphology to human cadaver dissection, human anatomy concepts and teaching strategies within the medical professional curriculum. Weekly lectures and discussions supplement a cadaver dissection-based course intended for students interested in pursuing an academic career in a medically related field.
Course Hours: H(2-6)
Prerequisite(s): Should have some previous experience with dissection. Consent of the instructors.

Medical Science 705

Advanced Methods in Health Research

Advanced health research designs (both quantitative and qualitative) and measurement techniques.
Course Hours: H(3-0)
Prerequisite(s): Medical Science 659.02. Admission to a graduate program in Community Health Sciences is normally required. Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other graduate and undergraduate students.

Medical Science 706

Theory and Practice of Family Therapy

Overview of different family therapy approaches focusing on systemic assessment and systemic intervention through therapeutic interviewing.Â The development of student knowledge and skills in family therapy utilizing social constructionist, narrative, systemic, collaborative, and pro-feminist ideas while fostering the professional identity of the therapist.

706.01 Theory and Practice of Family Therapy I: Systemic Approaches

706.02 Theory and Practice of Family Therapy II: Postmodern Approaches

Course Hours: H(3-0)
Prerequisite(s): This course is open to registered graduate students in medicine and the mental health professions, all others will require consent of the instructor.

Medical Science 707

Family Therapy Practicum

The development of conceptual and experiential expertise in working therapeutically with families.

707.01. Family Therapy I

707.02. Family Therapy II

Course Hours: H(2S-12)
Prerequisite(s): Consent of the Faculty.
NOT INCLUDED IN GPA

Medical Science 708

Theory and Practice of Interprofessional Psychosocial Oncology

Provides graduate students with a multidisciplinary introduction to the field of psychosocial oncology. Emphasis will be placed on understanding and interpreting the experience of cancer informed by theory, evidence and illness narratives. Case based learning in small interprofessional groups will allow students to explore a variety of key learning themes relevant to psychosocial oncology including distress assessment, depression, anxiety, adjustment and coping, sexuality, loss and grief. Attention to diversity will be integrated throughout the course.
Course Hours: H(3-0)
Prerequisite(s): Consent of Instructor. Must have an undergraduate degree in a relevant domain (including, but not limited to medicine, psychology, nursing, social work, spiritual care/theology).
Notes: This is an online course.

Medical Science 709

Advanced Epidemiology

Topics to include causal inference, epidemiologic measures, induction latent period, internal and external validity, control of confounding variables and interaction between study factors.
Course Hours: H(3-2)
Prerequisite(s): Medical Science 647.01. Admission to a graduate program in Community Health Sciences is normally required. Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other graduate and undergraduate students.

Medical Science 711

Systematic Reviews and Meta-Analysis

Exposes students to all steps involved in the conduct of a systematic review and meta-analysis.
Course Hours: H(3S-0)
Prerequisite(s): Medical Science 643.01, 643.02, 647.01 and 659.02, or consent of the instructor. Admission to a graduate program in Community Health Sciences is normally required. Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other graduate and undergraduate students.

Medical Science 712

Advanced Topics in Community Health Sciences Specializations

This senior level seminar series provides an opportunity to explore current topics within each of the specialization areas. Typically each course will explore three topic areas.

712.01. Advanced Topics in Biostatistics

712.02. Advanced Topics in Epidemiology

712.03. Advanced Topics in Health Services Research

712.04. Advanced Topics in Population/Public Health

712.05. Advanced Topics in Community Rehabilitation and Disability Studies

Course Hours: H(3-0)
Prerequisite(s): Enrolment is open to all MDCH graduate students. Consent of instructor is required for all other students.

Medical Science 713

Topics in Mountain Medicine and High Altitude Physiology

A tutorial-based course focused on high altitude medicine and physiology. The aim of the course is to introduce the students to the physiological adaptations of, and pathophysiology associated with, the hypoxia of altitude. Students will be introduced to several diseases associated with the hypoxia of high altitude (i.e., Acute Mountain Sickness; High Altitude Pulmonary Edema, High Altitude Cerebral Edema), and the pathophysiology underlying these diseases.
Course Hours: H(0-3T)
Prerequisite(s): Consent of Instructor.

Medical Science 717

Functional Genomics Technologies

An intensive "hands on" laboratory course supplemented with lectures that provides experience and theory underlying current techniques used in functional genomics research. Methods include DNA microarrays, bioinformatics analysis of DNA and protein sequences, retro-recombinant screening, gene marker and mutation analysis, gene product interactions and yeast two-hybrid screens, site-specific mutagenesis, mammalian expression systems and in situ hybridization. More conventional molecular biology methods involving plasmid preparation, Northern and Southern blotting techniques, PCR technology, restriction digestions, subcloning of DNA fragments, and others are included.
Course Hours: H(150 hours)
Prerequisite(s): Registration in the Master of Biomedical Technology program or one of Medical Science 537, 609.01, 609.02, 613.05 or equivalent, and consent of the Faculty.
Corequisite(s): Prerequisite or Corequisite: Medical Science 537 (Biochemistry 537) or equivalent.

Medical Science 721

Biochemistry and Molecular Biology

Historical and recent developments in analysis of eukaryotic genomes and control of gene expression, chromosome structure, bioinformatics, sequencing, proteomics, regulatory networks, metabolomics and related technologies and their applications to the study of human disease.
Course Hours: H(3-0)

Medical Science 731

Medical Education

The design, planning, teaching and evaluation of courses in the health science disciplines. Practical experience in teaching methods and curriculum development. Intended for graduate students, faculty and resident physicians, and approved for study credit by the College of Family Physicians of Canada.
Course Hours: H(1S-4)
Prerequisite(s): Consent of the Faculty.

Medical Science 733

Research Design and Statistics in Medical Education

Research design and statistical analysis including a broad overview of the variety of methods for research in medical education and related sciences. There is both a theoretical basis in lectures and seminars as well as applied approaches in laboratory exercises. A variety of research tools will be explored and utilized.
Course Hours: H(3-1)
Prerequisite(s): Consent of the Instructor.
Notes: Admission to the Medical Education specialization of the Medical Science graduate program is normally required for enrolment in this course.

Medical Science 735

Teaching Methods in the Medical Sciences

Examines traditional and innovative methods used in medical and science education and clinical teaching to enhance student and practitioner knowledge, skills and attitudes. Discussions and presentations will focus on the role of the teacher and teaching strategies that include the lecture, small group teaching, inquiry and problem solving methods, reflective tools, simulation, surgical skills, computer based instruction, bedside learning, one on one teaching and self-directed learning. The content will be presented within the context of contemporary research, practice and educational theory. Participants will be expected to identify, critique literature, and prepare instructional activities that link research and theory to practice.
Course Hours: H(3-0)
Prerequisite(s): Consent of Instructor.

Medical Science 737

Curriculum Design and Evaluation in the Medical Sciences

Presents an overview of the key elements of curriculum design and evaluation within the context of contemporary medical education research, learning and teaching theory, and teaching. Through classroom and electronic discussion, reading and assignments, participants will explore learning needs, objectives, the selection of teaching methods, the identification of resources, the implementation and monitoring of curriculum and evaluation.
Course Hours: H(3-0)
Prerequisite(s): Consent of Instructor.

Medical Science 739

Medical Education Measurement

Focuses on the assessment issues related to the measurement of student achievement, competency, and performance in educational settings. The principles of Classical Test Theory, Item Response Theory, and Generalizability Theory will be introduced and explored through both formal lectures and computer lab activities. Specifically, the course will focus on the measurement issues and concerns related to undergraduate and post-graduate medical education programs.
Course Hours: H(3-0)
Prerequisite(s): Consent of Instructor.

Medical Science 751

Topics in Medical Science

751.02. Cellular and Molecular Pathogenic Mechanisms of Diabetes

751.03. Biostatistics

751.07. The Physiological Development of the Fetus and Newborn

751.09. Ion Channel Diseases

751.18. Neural Control of Posture and Movement

751.30. Transdisciplinary Bone and Joint Health

751.31. Joint Injury and Disease Biomechanical Focus

751.41. Critical Perspectives in Proteomics.

Course Hours: H(3-0)
Prerequisite(s): Consent of the Faculty.

Medical Science 755

Directed Study

Lectures, seminars, term papers or training in theoretical and/or laboratory methods at the advanced level in the medical sciences.
Course Hours: H(1-6)
Prerequisite(s): Consent of faculty member who will supervise the chosen study.
MAY BE REPEATED FOR CREDIT

In addition to the numbered and titled courses shown above, the department may offer advanced level graduate courses specifically designed to meet the needs of individuals or small groups of students at the advanced doctoral level. These courses are numbered in the series 800.01 to 899.99. Such offerings are, of course, conditional upon the availability of staff resources.

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