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The flow of genetic information from DNA to final protein product. Gene structure and regulation of transcription, including gene structure and organization, chromatin structure, regulation of transcription and post-translational processing; and the activity of genes during development including stored messenger ribonucleoprotein particles and translational control in gametes, the switch from maternal to zygote genome control of development in early embryos and the molecular basis of morphogenesis and differentiation.

609.02. Genes and Development

Specialized topics including basic principles of infection; spread, prevention and control of infectious diseases; mechanisms of and approaches to study bacterial pathogenesis; mechanism, methodology and modelling of gene expression.

613.01. Epidemiology of Infectious Diseases

613.02. Pathogenesis of Microbial Disease

613.05. Regulation of Gene Expression in Bacteria

Introductory neuroscience courses covering aspects of cellular, molecular, and systems physiology, neuroanatomy, and neurodevelopment.

619.01. Cellular,ÌýMolecular and Developmental Neuroscience

619.02. Systems Neuroscience and Neuropathology

The action of chemicals and drugs on biological systems ranging from subcellular particles to the intact organism.

621.01. Basic Principles of Pharmacology

Respiratory physiology; including topics such as cellular, morphology, mechanics, control of breathing, and respiratory muscles, necessary to an understanding of respiration and respiratory failure. As well, core physiology and molecular biology underlying critical illness.

623.01. Pulmonary Mechanics and Gas Exchange

623.02. Physiology of Respiration and Critical Illness

623.03. Respiratory Science: Basic

623.04. Respiratory Science: Applied

Includes topics such as basic physiologic mechanisms including excitation-contraction coupling, mechanics, energetics, and cardiovascular control; major diseases entities as a means of illustrating pathologic alterations in normal physiologic mechanisms; or a systematic in-depth examination of the chemicals that affect the cardiovascular system.

629.01. Cardiovascular Physiology

629.02. Cardiovascular Pathophysiology

629.03. Cardiovascular Pharmacology

Advanced courses detailing the functional organization of the kidney at all levels, from cell to intact organism. Topics encompass basic physiological principles and their relevance to experimental medicine and therapeutics, as well as the study of disease processes, which impact kidney function.

633.01. Renal Physiology

633.02. Renal Pathophysiology

633.03 History of Renal Physiology

Physiology of the gastrointestinal (GI) tract at all levels from the cell to the intact system. Medical Science 637.01 has three components 1) An introductory series of lectures covering the basic physiological principles of the regulation of the GI tract and the individual organs that comprise it or are associated with it. 2) Extended directed tutorials conducted online through D2L. Topics will be selected to reflect the needs and interests of the enrolled students. 3) A written term paper on a subject of the students' own choice and pre-approved by the course co-ordinator that will also be presented orally to the class.

637.01. Organization and Function of the GI Tract

Introductory and advanced courses in immunology that cover humoral and cellular immunity and the inflammatory response at the cellular, molecular, and whole organism level. Basic mechanisms that lead to immunity or to inflammatory responses. The contribution of immunological and inflammatory processes in the immunopathogenesis of disease.

639.02. Cellular and Molecular

639.04. Inflammation

Advanced courses that provide in-depth coverage of the research discipline of genetics, including the areas of cytogenetics, genomics, metabolic genetics, mouse genetics, population genetics, and human and medical genetics.

641.01. Advanced Genetics I

641.02. Advanced Human Cytogenetics

641.03. Advanced Genetics II

641.04. Genomics

The principles of molecular and cell biology, pathology, physiology, pharmacology, microbiology and immunology as applied to new diagnostics, vaccines or therapeutics. Lectures in the two courses are in parallel and fully integrated. Both courses are required components of the MBT program. The goal of the course, with an emphasis on cellular and molecular mechanisms in health and disease, is to provide students with the skills to interface with individuals in these disciplines in the biotechnology industry. Complemented by special lectures that provide industry perspectives in these disciplines.

674.01. Physiological and Pharmacological Aspects of Therapeutics Development

674.02. Molecular Cell Biology of Diagnostic and Vaccine Development

An examination and discussion of current knowledge of the molecular and cellular biology of human cancer and the scientific basis of cancer therapy. Offered in a modular format: each course will consist of one required module and two elective modules. Students can choose the elective modules from a list that is specific for each course. Modules will emphasize student presentations, critical evaluation, and discussions of current and seminal research papers on the module topic. Refer to the Arnie Charbonneau Cancer Institute website at: for more information.

683.01. Cancer Pathology, Epidemiology and Therapy

683.02. Molecular Mechanisms of Cancer

683.04. Cell Biology of Cancer

Introduction to the theory and practical applications of medical imaging. Specific courses focus on an overview of modern diagnostic imaging techniques (689.01), as well as advanced study of specific techniques including magnetic resonance imaging (689.02) and medical image processing (689.03), and molecular imaging (689.04).

689.01. Medical Imaging Techniques

689.02. Advanced Magnetic Resonance Imaging

689.03. Advanced Medical Image Processing

689.04. Advanced Molecular Imaging

689.10. Medical Imaging Theory

689.11. Medical Imaging Applications

689.99. Medical Imaging Project

Overview of different family therapy approaches focusing on systemic assessment and systemic intervention through therapeutic interviewing. The development of student knowledge and skills in family therapy utilizing social constructionist, narrative, systemic, collaborative, and pro-feminist ideas while fostering the professional identity of the therapist.

706.01 Theory and Practice of Family Therapy I: Systemic Approaches

706.02 Theory and Practice of Family Therapy II: Postmodern Approaches

The development of conceptual and experiential expertise in working therapeutically with families.

707.01. Family Therapy I

707.02. Family Therapy II

Modular course offering advanced knowledge at the cellular, molecular, and whole organism levels including the hormonal regulation of the vascular system, the interaction between endothelium and smooth muscle in the blood vessel, the molecular mechanisms underlying smooth muscle contraction and relaxation, differentiation and dedifferentiation, and the pathogenesis of vascular diseases including hypertension and atherosclerosis. Drug treatments for vascular diseases and their molecular mechanisms will also be covered.

722.01. Vascular Biology
722.02. Vascular Pharmacology

An inquiry-based approach used to provide students with a broad background for the study of smooth muscle and to introduce students to current trends in the field. Students will also be introduced to the spectrum of research on smooth muscle ongoing at the ²ÝÝ®ÎÛÊÓƵµ¼º½. The subjects to be included range from the molecular biology and biochemistry of individual proteins to the function and regulation of integrated smooth muscle systems. A number of methodological approaches that are being used for the study of smooth muscle will also be discussed.

The primary goal is the technical skills of grossing a surgical specimen in a safe and appropriate manner. Secondary goals include skill development in quality management, ancillary techniques, frozen section cutting, and medical photography.

748.01. Surgical Pathology Practicum I

748.02. Surgical Pathology Practicum II

Hands on rotation that will train students how to perform autopsies under the supervision of a pathologist. Knowledge from anatomy, physiology, histology, and human pathology will be incorporated in the training.

749.01. Autopsy Pathology Practicum I

749.02. Autopsy Pathology Practicum II

Guided work with practical research, encouraging independent thought and collaboration with pathologists and clinical colleagues.Ìý Requires completion of written reports and oral presentation on research performed.

750.01. Pathologists' Assistant Research Project I

750.02. Pathologists' Assistant Research Project II

751.07. The Physiological Development of the Fetus and Newborn

751.09. Ion Channel Diseases

751.31. Joint Injury and Disease Biomechanical Focus

751.43. Orientation and Clinical Rotations for Pathologists’ Assistants